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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RB1CC1 All Species: 28.48
Human Site: S1285 Identified Species: 62.67
UniProt: Q8TDY2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q8TDY2 NP_001077086.1 1594 183091 S1285 D S T R G D S S S L V A E L Q
Chimpanzee Pan troglodytes XP_001149458 1594 182953 S1285 D S T R G D S S S L V A E L Q
Rhesus Macaque Macaca mulatta XP_001102620 1594 183007 S1285 D S T R E D S S S L V A E L Q
Dog Lupus familis XP_535068 1593 183137 S1284 E S T R E D S S S L V A E L Q
Cat Felis silvestris
Mouse Mus musculus Q9ESK9 1588 182346 S1281 E S A R E D S S S L V A E L Q
Rat Rattus norvegicus NP_001101371 1588 182209 S1281 E S A R E D S S S L V A E L Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001515279 1595 182705 S1289 E S T S E E S S S L V A E L Q
Chicken Gallus gallus XP_001232350 1598 182600 S1290 P S E S S A E S S L V A E L Q
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996156 1357 152264 S1085 I K L A P L P S R N A S R R E
Honey Bee Apis mellifera XP_391908 1303 147219 D1032 G L H K E S S D E Q L E M S Q
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P61430 856 99003 V585 I N S E K D K V E K I I K E L
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 98.4 95.3 N.A. 89 89.4 N.A. 81 79.7 N.A. N.A. N.A. 22.9 23.5 N.A. N.A.
Protein Similarity: 100 99.7 99.2 97.7 N.A. 94.1 94.4 N.A. 89.7 89.4 N.A. N.A. N.A. 42.8 41.2 N.A. N.A.
P-Site Identity: 100 100 93.3 86.6 N.A. 80 80 N.A. 73.3 60 N.A. N.A. N.A. 6.6 13.3 N.A. N.A.
P-Site Similarity: 100 100 93.3 93.3 N.A. 86.6 86.6 N.A. 86.6 60 N.A. N.A. N.A. 20 26.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 35.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 19 10 0 10 0 0 0 0 10 73 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 28 0 0 0 0 64 0 10 0 0 0 0 0 0 0 % D
% Glu: 37 0 10 10 55 10 10 0 19 0 0 10 73 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 19 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 0 0 0 0 0 0 0 0 10 10 0 0 0 % I
% Lys: 0 10 0 10 10 0 10 0 0 10 0 0 10 0 0 % K
% Leu: 0 10 10 0 0 10 0 0 0 73 10 0 0 73 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % N
% Pro: 10 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 82 % Q
% Arg: 0 0 0 55 0 0 0 0 10 0 0 0 10 10 0 % R
% Ser: 0 73 10 19 10 10 73 82 73 0 0 10 0 10 0 % S
% Thr: 0 0 46 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 10 0 0 73 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _